Instructions for use:
Streptocide is an antimicrobial drug belonging to the group of chemotherapeutic drugs with bacteriostatic action against streptococci, gonococci, meningococci, Escherichia coli, pneumococci and other bacteria.
Composition and form of release
The drug is produced in the following dosage forms:
- White tablets containing 300 and 500 mg of streptocide, in packs of ten;
- Streptocidal ointment 5% and 10% on a vaseline basis, in tubes of 25, 30 or 50 g;
- Suspension 5% containing streptocide 5 g, thymol 0.5 g, distilled water 69.75 g, and emulsifier 20 g;
- Liniment 5%, which includes streptocid 5 g, animal fat 3.1 g, lime water 57.9 g, fish oil 34 g, in jars of 25 or 30 g.
Streptocid analogs
Structural analogues of Streptocide for the active substance: Streptonitol, Osartsid, Sulfanilamide.
In addition, the following preparations of Streptocide are produced:
- Streptocid soluble in the form of a white powder. This analogue of Streptocid, due to its good solubility in water, can be used not only inside, but also intramuscularly, subcutaneously and intravenously;
- Sunoref ointment, which contains streptocid, eucalyptus oil, sulfadimezin, camphor, ephedrine hydrochloride, norsulfazol. The ointment is applied topically for the treatment of chronic and acute rhinitis.
pharmachologic effect
According to the instructions, Streptocide has a bacteriostatic effect. In terms of its effectiveness, the drug is largely inferior to modern antibiotics. Currently, many strains of microorganisms, in particular hospital ones, are resistant to treatment with streptocide.
The drug acts on gram-negative and gram-positive cocci, chlamydia, gram-negative rods, nocardia, protozoa. In an alkaline environment, the activity of streptocide increases.
Anaerobes, Pseudomonas aeruginosa, enterococci are immune to treatment with streptocide.
When Streptocide is used orally, it is rapidly absorbed, after 1-2 hours its maximum concentration in the blood plasma is observed.
With the advent of more active and much more easily tolerated sulfanilamide drugs and antibiotics, the value of the drug as a drug for the treatment of bacterial infections has decreased significantly.
Indications for the use of Streptocide
According to the instructions, Streptocid is shown:
- with chronic and acute gonorrhea;
- with wound infections;
- with colitis;
- with epidemic cerebrospinal meningitis;
- with angina and various coccal infections;
- with pyelitis;
- with colibacillary cystitis.
Treatment with Streptocide is especially effective for infections caused by beta-hemolytic streptococcus (puerperal sepsis, erysipelas, streptococcal pneumonia, etc.).
How to use Streptocide
According to the instructions, Streptocid is prescribed orally for bacillary and coccal diseases. As a rule, the dosage for adults is 0.5-1 g per dose four to six times a day, but not more than seven times.
In case of wound infections with a purulent complication, for the treatment of infected burns, the introduction of a powder, liniment or Streptocide ointment into the wound is prescribed.
The maximum dosage of the drug for adults:
- 2 g - single;
- 7 g - daily.
Contraindications
The use of Streptocide is contraindicated in:
- severe liver or kidney failure;
- anemia;
- porphyria;
- azotemia;
- congenital deficiency of glucose-6-phosphate dehydrogenase;
- pregnancy and breastfeeding;
- hypersensitivity to the components of the drug.
Treatment with Streptocide is contraindicated in newborns, as it causes kernicterus.
The drug in the form of tablets is contraindicated in children under three years of age.
Side effects of Streptocide
The instructions for Streptocid indicate the following side effects:
- Hematopoietic system: thrombocytopenia, hemolytic anemia.
- Allergic reactions: urticaria, anaphylactic shock, pruritus, Stevens-Johnson syndrome, Lyell's syndrome.
- Urinary system: crystalluria with acidic urine.
- Gastrointestinal tract: transient changes in liver enzymes, vomiting, nausea.
Overdose
Overdose symptoms are as follows: headache, vomiting, nausea, cyanosis, dizziness.
In case of overdose, symptomatic therapy should be carried out.
Drug Interactions Streptocide
When treating with a drug or an analogue of Streptocid, it must be borne in mind that novocaine and other drugs with a similar chemical structure containing a para-aminobenzoic acid residue may exhibit an antisulfanilamide effect.
Storage conditions
The drug is stored in a dry dark place. The shelf life of Streptocide tablets is ten years, ointments - four years, liniment - one and a half years.
Streptocid is an antimicrobial drug with a wide spectrum of action. Most often, it is used for various injuries of the skin, contributing to faster disinfection and healing of wounds, treatment and infectious lesions of the mucous membranes of the body.
Streptocide components penetrate into the bacterial cell, disrupting its metabolic processes, resulting in a decrease and suppression of the growth of pathogenic microorganisms.
Streptocid is available in various forms: tablets, powder and ointment. The composition of the drug contains the main active ingredient - sulfanilamide.
The main problems in which the use of streptocide will help:
- Powder and ointment are used externally for the treatment of festering wounds, infected burns of the first and second stages, purulent and inflammatory processes of the skin, boils, carbuncles, acne.
- Tablets are used for internal use for sore throats and any infectious lesions.
The shelf life of streptocide,usually does not exceed five years. Streptocid can be purchased at any pharmacy without a prescription.
Streptocid in the form of tablets should be taken according to the recommended dosage:
- Children (6-12): use 0.3 grams four times a day, do not exceed the daily dose of the drug - 1.2 grams.
- Children (from 12 and adults): use 0.3-0.6 grams three times a day, do not exceed the daily dose of the drug - 2.4 grams.
Streptocid is able to be absorbed into the blood within one to two hours after application. Up to 95% of the drug is excreted by the kidneys within 16 hours after application. The duration of streptocide intake should be adjusted by the doctor, but, as a rule, it is not used for more than seven days.
Tablets can also be used for external use, after grinding them into powder. The result of the action of streptocide is the cessation of the release of purulent masses from the wound, as well as the formation of a crust that will cover the affected area.
Streptocid in the form of a powder is used exclusively externally, the drug is placed under a bandage on the wound area.
The bandage must be changed daily.Recommended dosage:
- Children (3-12): use 0.3 grams per day.
- Adults: use 5 grams, the maximum daily dose is 15 grams.
The ointment is used exclusively externally, for the treatment of wounds under a bandage. The dressing is changed daily.Streptocide should be stored in a dry and dark place, away from children.
Side effects and contraindications
The use of streptocide can cause the following side effects:
- Nausea accompanied by vomiting.
- Diarrhea.
- Allergic reactions (dermatitis, urticaria).
- Leukopenia/thrombocytopenia.
- Anemia.
- Myocarditis/tachycardia.
- Seizures.
- Hypoglycemia.
- Visual/sleep disturbances.
- Headaches.
- Vertigo.
If one or more side effects are detected, the drug should be stopped immediately. In case of an overdose of the drug, gastric lavage should be carried out and an enterosorbent should be taken. In severe cases, hemodialysis may be needed.
Streptocid can not be used in the presence of:
- anemia
- Diseases of the kidneys and liver
- Azotemia
- Porfiria
- Pregnancy and lactation
- Diseases of the bone marrow and hematopoietic system
When infected with group A, since the drug is not able to act on bacteria of this type.
Content
According to the instructions for use, Streptocide powder is used to treat wounds, treat a runny nose, sinusitis, tonsillitis. The drug is sold without a prescription, has an antimicrobial effect, kills microorganisms, treats inflammatory processes of various etiologies. Streptocid can be used orally or externally, gargle, inhale to facilitate breathing.
What is streptocid powder
According to the pharmacological action and composition, Streptocid powder belongs to the group of sulfonamides, antimicrobial drugs for the treatment of skin diseases. Means of white color of crystalline texture has no smell, is a chemotherapeutic drug with a selective bacteriostatic effect. It finds application in inflammatory diseases of the throat, is used externally for the treatment of wounds or purulent lesions of the skin.
The effectiveness of the drug is manifested in relation to strepto-, meningo-, gono-, pneumococci, Escherichia coli, Proteus. Sulfanilamide inhibits the reproduction of pathogens of an infectious disease, which makes the body's defenses stronger. The drug belongs to the drugs of short-acting systemic use. It can be produced in the format of tablets, ointments, liniment.
Compound
Powdered Streptocid is available in 2, 5 or 10 g. This also changes the concentration of sulfanilamide (active ingredient). Known release form: laminated bags, paper bags, bottles, jars. In addition to the crystalline powder, the following types of drugs are distinguished:
- Tablets of 0.3 and 0.5 g of the active substance in planimetric packs of 10 pieces. The tablet contains 300 or 500 mg of sulfanilamide, starch, talc, stearic acid.
- Streptocid ointment - 5 or 10% on a vaseline basis. It is produced in jars, tubes, containers of 15, 25, 30 and 50 g. 5 or 10 g of streptocid per 100 g of ointment.
- Streptocide liniment - 5% concentration, 5 g of streptocide, additional substances are fish and animal fats, lime water. Release form - cans of 25, 30 and 50 g.
- Suspension of streptocide - 5%, contains 5 g of streptocide. Auxiliary components - emulsifier, thymol (sodium salicylate), distilled water.
- Soluble streptocide - 0.5 g, white powder, highly soluble in iodine, water. It is taken orally and parenterally, subcutaneously, intramuscularly, intravenously.
Properties of Streptocide
The crystalline substance Streptocid in powder according to the chemical formula refers to para-aminobenzenesulfamide. Odorless, white, poorly soluble in cold water and isotonic saline up to 0.8%. Medium soluble in ethyl alcohol, melting point - up to 170 degrees. The streptocide molecule consists of a sulfonamide group linked to aniline.
pharmachologic effect
The substance has an antimicrobial effect, is active against gram-positive and negative cocci. Applying the powder to damaged skin accelerates wound healing, helps erosions to epithelialize faster. The mechanism of action is based on the connection of compounds with para-aminobenzoic acid, which is necessary for the vital activity of bacteria.
Due to the similarity with this acid, sulfonamides penetrate into the protoplasm of bacteria, replace the substrate, and block the enzyme system. There is a violation of metabolic processes, microbes stop growing and multiplying due to the lack of folic acid intake. Sulfanilamide is active, rapidly absorbed from the gastrointestinal tract. It reaches its maximum concentration in a couple of hours, being found in the blood.
Four hours after taking Streptocid is found in cerebrospinal fluid, saliva, gastric juice, bile, urine. Part of the molecule under the action of enzymes becomes acetoform, which reduces the antimicrobial activity of the agent. This form is found in 10-20% concentration in the blood, in the urine - up to 50%. In eight hours, 50% of the drug is excreted by the kidneys.
Application
Indications for the use of Streptocide powder are the following factors, diseases of the body:
- infected superficial wounds;
- burns of the first, second degree;
- folliculitis;
- boils;
- carbuncles;
- acne vulgaris;
- erysipelas;
- stomatitis (used with tooth powder);
- the drug is prescribed for infectious and inflammatory processes on the skin;
- purulent wounds due to skin lesions by bacteria and infections;
- powder can even cure acne (sprinkle).
For wounds
Streptocide powder for wound treatment is popular. It is applied directly to the affected surface, making dressings every couple of days. In case of superficial damage, you need to pour the remedy on the wound, covering it completely. In addition to scratches, cuts and abrasions, purulent wounds can be treated with medicine, but it is better to do this in a hospital - doctors give such an argument to speed up healing.
From a cold
A ready-made powder or a crushed tablet of Streptocide can be used to treat a runny nose. Pour the drug into a clean teaspoon, alternately draw the substance into the nostrils. Do this carefully so as not to choke on the many small particles entering your throat. If it is inconvenient to inhale powder from a spoon, roll a tube out of paper. Treat at least six times a day for a course of 3-4 days. For 5-6 days, rhinitis disappears completely. A tablet or 2 g of powder is enough for a day.
With sinusitis
Doctors advise for uncomplicated sinusitis to use the following recipes using Streptocide:
- mix with Levomycetin in a ratio of 2: 1, divide into two parts, inhale in turn through the nostrils, repeat twice a day;
- dissolve 2 g of powder in a glass of warm water, drip into the nose;
- moisten cotton swabs with oil, roll in powder, insert into the nostrils, breathe through the nose;
- a mixture of 1.5 g of Streptocid and Norsulfazol, 25,000 units of Penicillin and 0.05 g of Ephedrine inhale through the nostrils up to four times a day;
- mix fish oil or baby cream with 1 g of powder, lubricate the nasal passages.
With angina
For the treatment of purulent tonsillitis, long-term non-healing wounds, aphthous stomatitis in young children, it is necessary to treat the damaged areas of the oral mucosa with powder and hold for 10 minutes or more. The sooner you start treatment with Streptocide, the less time it will take to recover. The powder is applied every two hours, the agent is applied topically. In the intervals during therapy, it is recommended to use mouth rinses with an antibacterial solution, which speeds up recovery.
Instructions for use of Streptocid powder
Each package of a broad-spectrum antibacterial drug is supplied with instructions for use, which contains basic instructions for using Streptocide. Some excerpts from it:
- the treatment requires a plentiful alkaline drink;
- if hypersensitivity reactions occur, therapy is discontinued;
- long-term treatment with the drug requires the necessary systematic monitoring of the blood picture, the functionality of the kidneys and liver;
- with caution it is recommended to use the drug in patients with impaired renal function;
- dispensed without a prescription, stored in a place protected from light and children;
- shelf life - 60 months;
- the permitted dosage of the antibiotic depends on age: adults 500 mg-1 g 5-6 times a day, children under one year old - 50-100 mg, 2-5 years old - 200-300 mg, 6-12 years old - 300-500 mg;
- the maximum daily dose for adults when taken orally is 7 g, single - 2 grams of sterile powder.
Outdoor use
To treat the cavity of wounds and mucous membranes, the medication is used externally. Purulent inflammation of the skin areas is sprinkled or powdered with powder in the amount of 5-15 g. They are used without a bandage, but cover the affected area with a gauze cloth, fix with a bandage. Dressings are carried out once a day, if necessary twice, if the separated exudate is uncomfortable and there is a lot of it.
For symptoms of sore throat or inflammatory processes in the mouth, external gargling with Streptocide in powder is used. It is dissolved with warm water and the procedure is carried out 5-6 times a day. You can additionally process the tonsils - they are sprinkled with powder, the mash is kept for five minutes. Then she spits, areas of the mucous membrane of the throat and oral cavity are treated with a disinfectant. The procedure is repeated every two hours.
Ingestion
Internal use of Streptocide is indicated for severe forms of dysentery, enteritis caused by bacterial pathogens. You can use the medicine for the onset of sore throat - mix with honey, take at night. For coccal or bacillary diseases, the drug is used in a dose of 0.5-1 g every 4-6 hours for adults, but not more than 6-7 g per day. The duration of the course and the exact dosage are determined by the appointment of a doctor, because with self-medication it is impossible to predict the toxic effect of the drug in relation to liver cells.
For kids
The use of Streptocid by children depends on the severity of the symptoms of the disease. For the treatment of angina, powdering the tonsils with a bag of powder, gargling, ingestion with honey or resorption is used (the child may refuse, because the medicine tastes bitter). The dosage of the drug depends on age, check the amount in the table:
During pregnancy
The drug is prohibited for use in the first and third trimesters of pregnancy, because it can cause unwanted toxic effects on the fetus. With lactation and breastfeeding, it is contraindicated for use, because it penetrates into breast milk and the baby's body. Children under one year of age should not take the medicine because of the increased risk of jaundice.
drug interaction
Instructions for use of the drug indicates that not all drugs can be used with it at the same time:
- myelotoxic agents enhance the effect of hematotoxicity of the drug;
- Novocaine and other drugs with a chemical structure containing para-aminobenzoic acid residues exhibit an antisulfanilamide effect, according to reviews, reduce the effect of treatment.
Side effects and overdose
Exceeding the dose of the drug contributes to the manifestation of adverse reactions and overdose effects, which are treated with abundant drinking, gastric lavage with a 2% solution of soda and activated charcoal, and taking enterosorbents. A large amount of sodium bicarbonate solution, forced diuresis, hemodialysis are effective in relation to the symptoms of an overdose. Side effects are:
- allergic reactions;
- headache, dizziness;
- nausea, vomiting;
- cyanosis, leukopenia;
- agranulocytosis, crystalluria;
- intestinal colic;
- drowsiness, depression, fainting, confusion;
- blurred vision, fever;
- anemia, jaundice.
Contraindications
The use of any form of medication is contraindicated if the following symptoms appear:
- hypersensitivity to components;
- anemia;
- kidney or liver failure;
- kidney or liver disease in the active stage;
- congenital deficiency of enzymes;
- azotemia, porphyria;
- pregnancy, breastfeeding;
- newborn children;
- tablets can not be used up to three years.
Allergy to streptocid
When applied externally, an allergy to Streptocid is possible, because sulfanilamide is considered a strong allergen. It is characterized by inflammation of the skin, the appearance of red spots, hives, itching and rashes. In severe cases, there may be a feeling of suffocation, anaphylactic shock and Quincke's edema. Treatment consists of:
- discontinuation of the drug (replacement with analogues);
- the use of antihistamines;
- with a complication - the administration of glucocorticosteroids.
Analogues
According to the structure, active substance and pharmacological action, the following analogues of Streptocide are distinguished - sulfanilamide preparations:
- Streptonitol;
- Osarcid;
- Sulfanilamide;
- Streptocide soluble;
- Sunoref ointment (contains, in addition to sulfanilamide, eucalyptus oil, camphor, ephedrine hydrochloride, sulfadimezin, norsulfazol - treats acute and chronic rhinitis).
Price
A medication for external use and its varieties can be found in any pharmacy, bought in an online store or ordered from a pharmacist from a catalog. The cost of drugs depends on the form of release. Approximate prices:
|
Variety |
Price when buying online, rubles |
Price in a pharmacy, rubles |
|
Powder, 2 g, 1 piece |
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|
Powder, 5 g, 1 pc. |
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|
Powder, 10 g, 1 pc. |
||
|
Soluble liniment 5%, 30 g |
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|
Ointment 0.1%, 25 g |
Video
Attention! The information provided in the article is for informational purposes only. The materials of the article do not call for self-treatment. Only a qualified doctor can make a diagnosis and give recommendations for treatment, based on the individual characteristics of a particular patient.
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Application of Streptocid powder
Streptocide can heal wounds, apply it for burns. Also, this powder medicine has a number of other indications for use.
Table of contents [Show]
Streptocide - description of the remedy
Streptocide is an antimicrobial drug from the group of sulfonamides, available in powder form, used for local therapy. It helps to remove the infectious and inflammatory process from the skin, mucous membranes. The active substance of Streptocid is sulfanilamide in the amount of 2.0 g. The drug does not contain additional components.
Other forms of release of Streptocide are ointment and liniment.
The powder is produced in weights of 2 and 5 g, packed in heat-sealed bags. It looks like a white mass containing crystals. Manufacturers of the drug - "Lekar", "Pharmstandard", "Ozone", "Meligen" and some others. The medicine costs about 30 rubles for one powder.
How does Streptocide work? It provides a bacteriostatic effect due to competitive antagonism with the most important proteins and enzymes of bacteria. The substance inhibits purines and pyrimidines, which are required for the synthesis of RNA and DNA of microbial cells. This interferes with reproduction, so the process of dividing microbes stops.
Sulfanilamide destroys pathogenic microbes that lead to the development of the inflammatory process. The active substance acts on the following bacteria:
- coccal flora - gram-negative, gram-positive;
- coli;
- shigella;
- clostridia;
- corynebacter;
- yersenia;
Also, the tool affects the reproduction of some protozoa, including Toxoplasma. When applied externally, the powder helps to heal wounds faster, accelerates the epithelization of erosions. All these properties determine the widespread use of the tool.
The drug can be used to treat many external pathologies caused by bacteria. You can not take the drug inside. Previously, Streptocide was produced in the form of tablets for oral administration, but now they have been replaced by more effective and safe drugs.
The medicine can be used for acute and chronic tonsillitis.
For sore throats, topical application or gargling will help relieve sore throats. In severe cases of the disease, Streptocide is indicated in complex therapy, with an average, mild course, it is used in monotherapy. The drug Streptocid in powder helps against various skin pathologies:
- boils and carbuncles, including multiple ones;
- acne, blackheads on the face;
In the nose, the medicine can be diluted and instilled with a runny nose with purulent discharge, which is accompanied by a pronounced microbial process. Before starting treatment, it is important to consider contraindications. For children from 3 years old, the drug is even locally prescribed with caution, it is preferable to use it in adulthood.
During pregnancy, lactation, treatment with Streptocid is prohibited. Also among the contraindications are kidney, liver failure, diseases of the blood and bone marrow, severe heart failure. Another contraindication is the lack of glucose-6-phosphate dehydrogenase. It is forbidden to use the remedy for porphyria, thyrotoxicosis.
Usually, compliance with dosages - how much and how often to use the drug - helps to prevent systemic side effects. But allergic reactions are possible, they often appear on sulfanilamide. Among them are observed:
- rash on the body;
- redness, red spots;
- hives;
- burning skin;
- manifestations of dermatitis.
Systemic absorption is possible in case of overdose, exceeding the dosage regimen or therapeutic course. In this case, it is possible to develop a headache, dizziness, a person may turn pale, feel sick and may vomit. Dyspepsia is also characteristic, it includes belching, heartburn, abdominal pain, bloating. Other side effects:
- skin cyanosis;
- excessive pallor;
- the appearance of salts in the urine;
- violation of the composition of granulocytes in the blood;
- change in kidney function;
- an increase in thyroid hormones;
- thrombocytopenia;
With the appearance of these effects, powder treatment should be urgently stopped. Further, it is important to consult a doctor and undergo, if necessary, symptomatic therapy.
The powder can be used in different ways depending on the indication and area of application. In the presence of wounds, burns with secondary infection, sprinkle the agent directly on the affected area. If the wound is deep, you can pour Streptocid into the wound. At the same time, contact with fingers is not allowed, and the medicine is scattered directly from the bag.
Dressings with Streptocide are performed regularly every 1-2 days, with purulent wounds - up to 3 times / day, with weeping wounds - up to 5 times.
For an adult, the maximum dosage is 15 g / day, 5 g is consumed at a time. For children, the maximum and single dose is the same, not more than 300 mg. Wounds are treated before they heal. With a bacterial rhinitis, the procedure for therapy is as follows:
- pour a little powder on a clean surface;
- using a finger, gently distribute the product inside the nasal passages;
Also in the treatment of rhinitis, a combination of Streptocid, Sulfathiozolone and Ephedrine is often used, which are mixed in equal parts and used to be drawn into the nasal passages. The norm of treatment is three times / day for 5 days.
For the treatment of abscesses, acne, pyoderma, they make the so-called talker with powder. Mix 50 ml of salicylic acid 2%, 7 g of Streptocide, 7 g of sulfur, 50 ml of boric alcohol. The composition is stored in the refrigerator, applied to the skin three times / day. Course - no more than 14 days.
Streptocid analogs
Among the analogues, it is worth mentioning a number of local preparations that also have an antimicrobial effect and are sold in the form of powders, solutions, ointments:
In therapy, it must be taken into account that some drugs increase the hemotoxicity of sulfanilamide. These are all myelotoxic drugs, as well as Digitoxin, Isoprenaline. Streptocid reduces the effectiveness of anesthetics, especially Novocaine. During the entire period of treatment, more alkaline mineral waters should be taken orally.
Streptocid (sulfanilamide) is an antibacterial drug, the first representative of sulfanilamide drugs.
The drug is active against streptococci, pneumococci, gonococci and other bacteria. Since the accidental discovery of penicillin in 1929, the era of antibiotics has begun in medicine. Streptocide was discovered one of the first.
It is used in the treatment of infectious and inflammatory diseases provoked by bacteria sensitive to the drug. Of the side effects of Streptocide, dyspeptic symptoms (nausea, vomiting, diarrhea), disorders of the hematopoietic system, and dermatological allergic reactions should be distinguished.
Broad-spectrum antibacterial agent.
Can be bought without a doctor's prescription.
How much does Streptocid cost in pharmacies? The average price is at the level of 65 rubles.
In pharmacies you can find ointment and powder. There are also such varieties of the drug as Streptocid white and Streptocide soluble liniment. Since 2008, streptocid tablets have not been produced or sold in Russia.
The active substance is sulfanilamide. Streptocid ointment also contains soft white paraffin as an additional component. The powder contains 0.5 mg of sulfanilamide.
The substance has an antimicrobial effect, is active against gram-positive and negative cocci. Applying the powder to damaged skin accelerates wound healing, helps erosions to epithelialize faster. The mechanism of action is based on the connection of compounds with para-aminobenzoic acid, which is necessary for the vital activity of bacteria.
Due to the similarity with this acid, sulfonamides penetrate into the protoplasm of bacteria, replace the substrate, and block the enzyme system. There is a violation of metabolic processes, microbes stop growing and multiplying due to the lack of folic acid intake. Sulfanilamide is active, rapidly absorbed from the gastrointestinal tract. It reaches its maximum concentration in a couple of hours, being found in the blood.
Four hours after taking Streptocid is found in cerebrospinal fluid, saliva, gastric juice, bile, urine. Part of the molecule under the action of enzymes becomes acetoform, which reduces the antimicrobial activity of the agent. This form is found in 10-20% concentration in the blood, in the urine - up to 50%. In eight hours, 50% of the drug is excreted by the kidneys.
The drug is used in the treatment of the following infectious and inflammatory diseases, which are caused by microorganisms sensitive to the action of the drug:
- impetigo;
- carbuncles;
- erysipelas;
- pyelitis;
- cystitis;
- sore throats;
- enterocolitis;
- boils;
- infectious diseases of the mucous membranes and skin.
Also, this remedy is used in the complex therapy of infected burns (I–II stage), purulent wounds and other purulent-inflammatory processes of the skin.
Streptocid tablets are prescribed for infectious diseases of the skin, upper respiratory tract, respiratory and urinary tract, wound infections.
Severe renal failure, blood diseases, deficiency of glucose-6-phosphate dehydrogenase, nephrosis, nephritis, acute porphyria, thyrotoxicosis, I and II trimesters of pregnancy, lactation, hypersensitivity to sulfonamides.
The contraindications to the drug indicate that Streptocid during pregnancy and lactation is prohibited. The active substance of the drug quickly passes through the placental barrier and is found in the blood of the fetus. In addition, it can cause toxic effects.
When breastfeeding, the drug can provoke kernicterus in infants.
As indicated in the instructions for use, Streptocide powder can be applied externally to the damaged surface of the skin or blown into deep wounds. Also, in a mixture with Sulfathiazole, Benzylpenicillin and Ephedrine, Streptocide is used for nasal retraction in acute rhinitis.
If the wound is deep, then Streptocide powder is blown directly into it. At the same time, 5-15 g of powder is taken for one injection, depending on the size of the wound. After blowing the powder, the wound is usually covered with a bandage. The powder is blown in 1-4 times a day, depending on the intensity of the discharge from the wound, guided by the rule: the more the wound gets wet, the more often the powder should be blown into it. Powder is applied to wounds until they begin to heal or until the release of pus or inflammatory fluid from the wound surface stops.
One of the effective remedies in the fight against acne is Streptocide. It is a good antiseptic and destroys pathogenic microflora. For the treatment of skin rashes, streptocid ointment is most often used. The drug in the form of a powder is more suitable for the manufacture of lotions and masks. Before using the ointment, wash your face and wipe it with tincture of calendula.
Then apply ointment to each pimple (do this twice a day for 2 weeks). You can also use tablets: crush 20 pieces into powder and mix with aloe juice to the consistency of sour cream, add a couple of drops of iodine. Apply this mixture on your pimples at night and wash off with plain water in the morning. If the use of Streptocide does not help, then it is necessary to consult a doctor so that he can identify the cause of acne (this may be a hormonal surge, blockage of pores, or disruption of the digestive tract).
When using the drug, allergic reactions are possible, in addition, the following side effects are observed: headache, paresthesia, nausea, dyspepsia, agranulocytosis, cyanosis, dizziness, tachycardia, vomiting, leukopenia, crystalluria.
Tablets can also cause diarrhea, and in rare cases, nephrotoxic reactions, thrombocytopenia, hypoprothrombinemia, eosinophilia, visual impairment, peripheral neuritis, hypothyroidism, ataxia.
Overdose symptoms are as follows: headache, vomiting, nausea, cyanosis, dizziness.
In case of overdose, symptomatic therapy should be carried out.
In the treatment of patients with pathologies of kidney function, Streptocide is used with caution. The amount of fluid consumed during the treatment period should be increased.
When treating with a drug or an analogue of Streptocid, it must be borne in mind that novocaine and other drugs with a similar chemical structure containing a para-aminobenzoic acid residue may exhibit an antisulfanilamide effect.
We suggest that you read the reviews of people who used the drug Streptocid:
- Victoria. Streptocide is always in my first aid kit. I have two children, they often have abrasions and wounds after playing outdoors. Streptocide should be sprinkled on wounds so that they do not fester. You can also dilute the streptocide with water and wipe the walls with mold, it perfectly removes.
- Andrei. This is a proven tool. I often go camping and like to take this powder with me. It heals open wounds well and disinfects them, which is very important when there is nothing else at hand. But the problem is that finding this drug is not so easy. You run half the city before you buy. This has become a rarity, surprised, as an excellent tool
- Lera. I remember my mother in childhood treated our knees first with hydrogen peroxide, then poured streptocide powder. Vavki healed faster, they didn’t leave terrible scars. They say he is now sold in the form of a powder. I used to remember that it was in dark bottles, but now they say that it is in bags. By the way, he did not pinch when he hit the wound, which is very important for children. So I still recommend it to everyone.
According to the structure, active substance and pharmacological action, the following analogues of Streptocide are distinguished - sulfanilamide preparations:
- Streptonitol;
- Osarcid;
- Sulfanilamide;
- Streptocide soluble;
- Sunorfe ointment (contains, in addition to sulfanilamide, eucalyptus oil, camphor, ephedrine hydrochloride, sulfadimezin, norsulfazol - treats acute and chronic rhinitis).
Before buying an analogue, consult your doctor.
Keep out of the reach of children at a temperature not exceeding 25 °C. The shelf life of the liniment is 4 years, the powder for external use, ointments and tablets is 5 years.
is an antimicrobial drug of the group
sulfonamides
for external and local use. Streptocid is used to treat infectious and inflammatory diseases of the skin and mucous membranes, such as tonsillitis, infected wounds, burns,
folliculitisfuruncles
impetigorozh
Strictly following the letter of the rules, it must be assumed that the funds listed above with different names are varieties of Streptocide. However, the above different names belong to the same drug - Streptocide. Different names of the same medicine are due to the fact that some pharmaceutical factories produce medicine under historically established names. In fact, all Streptocides, regardless of the name, contain the same active substance and are produced in the same dosage forms, so there is no difference between them, except for the names. Given this state of affairs, in the future text of the article we will use the same name "Streptocid" for all drugs produced under different historical names.
Streptocide is currently available in Russia in the following dosage forms:
- Ointment 10%
- Liniment 5% for external and local use;
- Powder for external use.
Under the name "Streptocide" a powder and ointment are produced, under the name "Streptocide ointment", respectively, an ointment, and under the name "Soluble Streptocide" - liniment.
In the form of tablets Streptocide is not currently produced in Russia and Belarus, although such a dosage form existed in the past. However, in Ukraine, Streptocid is still available in tablets for oral administration. Also currently does not exist in Russia and Belarus, but in the past it was produced "Streptocid soluble" in powder form for the preparation of solutions for intravenous administration. Streptocid in tablets and in the form of intravenous injections was used to treat tonsillitis, erysipelas, cystitis, pyelitis, enterocolitis, wound infection and other infectious and inflammatory diseases of various organs caused by pathogenic microorganisms. Streptocide for oral and intravenous administration was no longer produced and used, since more effective drugs appeared (antibiotics and other, newer and more effective drugs of the sulfonamide group). Accordingly, currently in Russia and Belarus, Streptocide is produced and used only in forms for external and local use, and in Ukraine the drug continues to be used in dosage forms for external use and for oral administration.
Given the fact that the forms of Streptocide for oral administration are outdated, and in Ukraine they are produced mostly by inertia, we will consider various aspects of using only ointment, liniment and powder for external use. And we will not give various aspects of the use of Streptocid tablets, since this is impractical. After all, Streptocide tablets are too outdated, because in order to achieve the desired therapeutic effect, they must be taken in very high doses, which leads to a high risk of side effects. Currently, other drugs of the sulfonamide group are being produced, which, compared with Streptocide, are much more effective and with fewer side effects (for example, Biseptol, Sulfamethoxazole, Sulfadimethoxine, etc.).
All currently existing dosage forms of Streptocide contain as an active substance sulfanilamide. Moreover, the ointment and powder contain the usual sulfanilamide, and the liniment contains a soluble form of sulfanilamide, which is also called mesulfamide.
Powder for external use contains only the active substance itself - sulfanilamide, and does not contain auxiliary components, unlike ointment and liniment. The ointment also contains sulfanilamide in the amount of 10 g per 100 g of the finished product, and liniment - 5 g per 100 g of the finished product. Accordingly, Streptocide ointment has a 10% concentration, and liniment - 5%. Streptocide ointment contains medical vaseline as auxiliary components, and liniment contains glycerin, purified water and an emulsifier (Lanette SX, Neowax SX).
Streptocid powder is available in heat-sealed bags of 2 g or 5 g, and is a white powdery mass. Ointment 10% is available in aluminum tubes or dark glass jars with a volume of 25 g or 50 g, and is a homogeneous thick mass of white or light yellow color. Liniment 5% is available in aluminum tubes or dark glass jars with a volume of 30 g, and is a homogeneous thin mass of white or white with a creamy tint.
Rp.: Streptocidi 10% unguentum
In the recipe after the abbreviation "Rp." the name of the drug in Latin "Streptocidi" follows, then its dosage form and concentration are indicated (also in Latin): "10% unguentum". On the second line after the abbreviation "S." indicates how to use the prescribed remedy. The second line of the prescription is an indication for the patient.
Recipe for Streptocide liniment is written as follows:
Rp.: Streptocidi 5% linimentum
S. Lubricate wounds 3-4 times a day.
In the prescription, the first line indicates in Latin the name of the drug (Streptocidi), its dosage form (linimentum) and concentration (5%). The second line tells the patient how to use the medicine prescribed by the doctor.
Recipe for Streptocide Powder is written as follows:
Rp.: Streptocidi pulvis 5 g
S. Powder wounds 3 to 4 times a day.
In the prescription, in the first line, the doctor in Latin indicates the name and dosage form of the drug (Streptocidi pulvis - Streptocide powder), and in the second line - a brief prescription for the patient on how to use the remedy.
Streptocide has a detrimental effect on gram-positive and gram-negative cocci (spherical bacteria), such as streptococci, staphylococci, pneumococci, meningococci, gonococci, enterococci, etc. In addition, Streptocide is detrimental to the following microorganisms:
- Escherichia coli;
- Shigella spp.;
- Vibrio cholerae;
- Clostridium perfringens;
- Bacillus anthracis;
- Corynebacterium diphtheriae;
- Yersinia pestis;
- Chlamydia spp.;
- Actinomyces israeli;
- Toxoplasma gondii.
Accordingly, all dosage forms of Streptocide can be used to treat infectious and inflammatory diseases of the skin or mucous membranes of the mouth and nose caused by any of the above microbes.
Since the drug has an antimicrobial effect, it indirectly also has an anti-inflammatory effect due to the death of microbes that provoked an infectious-inflammatory process.
In addition to anti-inflammatory and antimicrobial action, Streptocide promotes faster healing of wounds on the skin.
So, Streptocid powder, Streptocid ointment and Streptocid (soluble) liniment are indicated for use as part of complex therapy for the treatment of the following diseases:
- Tonsillitis;
- Infected wounds of the skin (festering wounds);
- Burns of I-II degrees;
- Ulcers on the skin of various origins (including trophic ones);
- Erysipelas;
- Cracks in the skin;
- Purulent-inflammatory skin diseases, such as folliculitis, boils, carbuncles, acne vulgaris, impetigo, pyoderma, etc.
The powder is applied to the damaged surface of the skin by powdering, that is, first a little powder is poured onto the gauze, after which the surface of the wound is “powdered” with this gauze. You can also gently pour the powder directly from the bag onto the surface of the wound. But at the same time, you should try to evenly distribute the powder over the surface of the wound. After applying the powder to the damaged surface, it can be covered from above with a gauze cloth, dressed or left uncovered. For a single application to the wound, take 2-5 g of powder, depending on the size of the damage.
The powder can be applied to the wound surface 3-4 times a day. In this case, the frequency of application of the powder is determined by the course of the infectious-inflammatory process. For example, if the wound is weeping, with abundant discharge, then powder is often sprinkled on its surface, up to 4 times a day. If the wound is dry, then it can be treated with Streptocid powder only 1-2 times a day. In such a situation, it is recommended to apply Streptocide powder 1 time per day if the wound is then closed with a bandage, and 2 times a day if the wound is left open.
If the wound is deep, then Streptocide powder is blown directly into it. At the same time, 5-15 g of powder is taken for one injection, depending on the size of the wound. After blowing the powder, the wound is usually covered with a bandage. The powder is blown in 1-4 times a day, depending on the intensity of the discharge from the wound, guided by the rule: the more the wound gets wet, the more often the powder should be blown into it.
Powder is applied to wounds until they begin to heal or until the release of pus or inflammatory fluid from the wound surface stops.
In acute rhinitis, Streptocide powder is mixed with Sulfathiazole, Benzylpenicillin and Ephedrine, and is drawn in by the nose when inhaling. This powder mixture can be used for several days (5 - 7) to treat the common cold. In this case, the mixture is drawn into the nose several times a day, carrying out this procedure when an abundant discharge from the nose reappears.
The wound treated with ointment or liniment is closed with a gauze bandage, which is changed once every 1 to 2 days. Ointment or liniment is applied until pus or inflammatory fluid ceases to stand out from the wound, and it begins to heal.
The ointment or liniment is applied to the mucous membranes 2-3 times a day at regular intervals until the wound heals, or until the severity of the inflammatory process decreases.
For extensive wound surfaces, it is necessary to take into account that the maximum daily dosage of preparations for the treatment of lesions is 6 g of sulfanilamide (for adults). This amount of sulfanilamide (6 g) corresponds to 120 g of liniment or 60 g of Streptocide ointment. The maximum daily dosage of Streptocid preparations for external and local use for children 5-12 years old is 3 g of sulfanilamide (which corresponds to 60 g of liniment or 30 g of ointment), for children 1-5 years old - 1.8 g of sulfanilamide (which corresponds to 36 g of liniment or 18 g of ointment), and for children under 1 year old - 0.6 g of sulfanilamide (which corresponds to 12 g of liniment or 6 g of ointment). This daily dosage limit means that within 24 hours for the treatment of wounds and inflammatory elements, you can use no more than 120 g of liniment or 60 g of ointment for adults and adolescents over 12 years old, no more than 60 g of liniment or 30 g of ointment for children 5 - 12 years, no more than 36 g of liniment or 18 g of ointment for children 1-5 years old and no more than 12 g of liniment or 6 g of ointment for children under one year old. The limitation of the daily dosage for the treatment of extensive wound surfaces is due to the fact that the active substance from damaged skin and mucous membranes is easily absorbed into the bloodstream, and can have a systemic effect and provoke the development of severe systemic side effects.
On average, the course of application of Streptocide ointment or liniment is 10 to 14 days, however, if necessary and on the advice of a doctor, you can extend the use of the drug. Without the recommendation of a doctor, do not use liniment or ointment for more than two weeks in a row.
With the development of allergic reactions, the use of Streptocid should be immediately discontinued.
During the entire period of application of the ointment, powder or liniment of Streptocid, it is necessary to drink a large amount of alkaline liquids (for example, alkaline mineral waters, such as Borjomi, Essentuki 4, Slavyanovskaya, etc.).
If an ointment, liniment or powder is accidentally ingested (for example, by accidental swallowing), the stomach should be washed out as soon as possible, after which alkaline liquids should be drunk abundantly during the day (for example, mineral water Borjomi, Essentuki 4, Smirnovskaya, Nabeglavi, Luzhanskaya, etc. .d.).
With prolonged use of Streptocide ointment, powder or liniment, it is necessary to regularly take a general blood test, as well as monitor the condition of the liver and kidneys.
An overdose is manifested by the following symptoms:
- Headache;
- Nausea;
- Vomit;
- The phenomena of dyspepsia (heartburn, belching, flatulence, etc.);
- intestinal colic;
- Dizziness;
- Drowsiness;
- Depression;
- fainting;
- confusion;
- visual impairment;
- Fever;
- Hematuria (blood in the urine);
- Leukopenia (decrease in the total number of white blood cells in the blood);
- Agranulocytosis (disappearance of neutrophils, basophils and eosinophils from the blood);
- Thrombocytopenia (decrease in the total number of platelets in the blood) - observed only with prolonged overdose;
- Megaloblastic anemia - observed only with prolonged overdose;
- Jaundice - observed only with prolonged overdose.
For the treatment of an overdose, it is necessary to cancel the use of Streptocide and drink alkaline drinks abundantly for several days.
(for example, Borjomi, Essentuki 4, Smirnovskaya, Nabeglavi, Luzhanskaya, etc.). You need to drink alkaline mineral waters until all the symptoms of an overdose have passed.
Interaction with other drugs Ointment, liniment and powder Streptocid, when used to treat large wound surfaces or when used for a long time, when sulfanilamide can be absorbed into the systemic circulation, can increase the toxic side effects on the blood system of any other drugs that have hematotoxicity.
In addition, if Novocain and Streptocid are used one after another, this reduces the effectiveness of the latter. Therefore, if necessary, the simultaneous use of Novocaine and Streptocide should be maintained at least half an hour between their use. With other external agents, ointment, liniment and Streptocid powder do not interact with significant effects.
Against the background of the use of ointment, liniment or Streptocid powder, it is recommended to stop using the following drugs:
- Digitoxin;
- Isoprenaline;
- Caffeine;
- Phenylephrine;
- Phenobarbital;
- Adrenalin;
- Hydrochloric acid.
The safest for use in children is Streptocide liniment. And ointment and powder, compared to liniment, are more dangerous, because they contain a larger amount of active substance. Liniment can be used without fear for children from the age of three months, and ointment and powder - from the age of three. For children from birth to three months, liniment can also be used, but with caution, in minimal dosages and only under medical supervision. Accordingly, the ointment and powder can also be used to treat infectious and inflammatory diseases of the skin and mucous membranes of the mouth and nose in children under 3 years of age, but with caution and under the supervision of a doctor.
When used in children, it is necessary to strictly adhere to the maximum allowable dosages and terms of use in order to avoid overdose.
It is undesirable to use Streptocid ointment, liniment and powder for treating large surfaces in children so that the active substance is not absorbed into the bloodstream and does not cause systemic side effects.
With the appearance of systemic side effects, it is necessary to stop the use of Streptocid in children.
Ointment, powder and liniment in children are used in the same way as in adults.
To prepare the talker, mix 50 ml of a 2% solution of salicylic acid, 50 ml of boric acid, 7 g of Streptocid powder and 7 g of precipitated sulfur. All components are thoroughly mixed, and the finished composition is stored in a dark glass jar.
The talker is applied to the affected areas of the skin once a day in the evening, before going to bed, after cleansing the skin. 5 minutes after applying the talker, you can lubricate your face with a moisturizer.
Chatterbox with Streptocid can be used both for the treatment and for the prevention of acne, acne and pustular skin rashes. However, you can not use the talker for a long period of time without interruption. It is recommended to use one portion of the manufactured mash, and then take a break for a month, after which you can again conduct a course of therapy with a self-made remedy.
Streptocide and Salicylic acid Streptocide and salicylic acid in the form of a mixture are used to treat and prevent acne, acne and pustular lesions of the skin. Streptocid destroys pathogenic microbes that cause an infectious and inflammatory process on the skin, and salicylic acid reduces the production of sebum and promotes wound healing. Accordingly, a mixture of Streptocide with salicylic acid is an effective treatment for acne and blackheads.
To prepare the composition, add 5 g of Streptocide powder to 50 ml of 2% salicylic acid, mix thoroughly and place in a dark glass jar for storage. This composition should be applied to previously cleansed skin in the evening, before going to bed, once a day.
A solution of Streptocide in salicylic acid should be used in courses lasting up to one month. After the end of the course of therapy, you need to take a break (at least a month), after which you can use the solution again.
To prepare the talker, you need to mix 30 ml of salicylic acid, 2 g of Streptocid powder and 4 Levomycetin tablets powdered into powder. The finished composition is placed in a dark glass jar and stored for no longer than 1 - 2 months.
The talker is applied to the affected areas of the skin once a day in the evening, before going to bed, after preliminary cleansing of the skin.
Streptocide from the throat (with sore throat) Currently, Streptocide powder is used to treat pain and inflammation in the throat (for example, pharyngitis, ulcers, etc.) and tonsillitis. In the past, Streptocid tablets for oral administration were also used to treat angina, but they are not currently used, since there are more effective and safer means, including those from the group of sulfanilamide drugs, such as Biseptol, Sulfadimetoksin, etc.
Streptocid powder for the treatment of sore throat can be used in three ways - they are sprinkled with tonsils, dissolved in the mouth or gargled. For sprinkling, a small amount of powder is taken and applied to the tonsils (it is convenient to do this with an ordinary cotton swab), after which you should try not to swallow saliva, eat or drink for 10 minutes so that the drug remains on the mucous membranes. After 10 minutes, the powder is spit out and the throat is gargled with any disinfectant solution, for example, chlorhexidine, furacilin, etc. Such treatment of the throat (sprinkling with Streptocide powder + gargling with a disinfectant solution) is carried out every 2 hours.
For resorption in the mouth, you can use pure Streptocide powder or mixed with honey. Pure powder is poured into a teaspoon (about 1/4 - 1/2 spoon), then licked off and held in the mouth until completely dissolved. Unfortunately, the absorption of pure Streptocide powder brings discomfort, since the drug is bitter. Therefore, to eliminate an unpleasant bitter taste, Streptocid powder is often mixed with honey. The resulting mixture is absorbed as long as possible in the oral cavity. After complete resorption of pure powder or mixed with honey, it is necessary to refrain from eating and drinking for 20-30 minutes so that the medicine stays longer on the mucous membranes. To treat a sore throat, it is necessary to dissolve a mixture of honey with Streptocide or pure powder 2 to 3 times a day.
In addition, you can dissolve Streptocide powder in warm water, and gargle with the resulting solution. To prepare a solution for rinsing, take 2 g of powder in a glass of warm water. Rinsing is done every 2 hours.
More about angina
Streptocide ointment or liniment for the treatment of acne and acne is recommended to simply be applied to the skin as a cream 1 to 2 times a day after cleansing the skin. The ointment or liniment is left on the skin overnight or for several hours if the drug was applied during the daytime. If there are few acne or blackheads, then these funds can be applied pointwise, directly on the rash.
And the powder immediately after washing just powder the skin. To do this, after washing, the skin is allowed to dry so that it does not become wet, but slightly moist, after which Streptocid powder is collected on the fingertips, and with patting movements it is gently distributed over the entire problem area of the skin. Dusting with Streptocide powder is performed 1 time per day in the evening, before going to bed. The applied powder is left overnight and washed off in the morning.
Streptocid quickly eliminates redness, reduces swelling and stops the inflammatory process. Thanks to this action, pimples and blackheads present on the skin are resolved within a short period of time, and new rashes do not appear.
The drug is used in courses lasting 2 to 4 weeks, after which they take a break for a month and, if necessary, repeat the course of treatment. Streptocid can also be used sporadically when skin rashes are already mostly cured, but sometimes single pimples or blackheads appear. In such cases, the ointment, powder or liniment is used for several days to quickly eliminate the rashes that have appeared.
In addition, Streptocide for the treatment of acne and acne can be used not in its pure form, but in the form of a mash prepared on the basis of salicylic acid. The recipe for the preparation and rules for using such talkers are given in the relevant sections. However, the effectiveness of the talker and Streptocid in its pure form for the treatment of acne and blackheads is approximately the same.
More about acne
The powder is poured directly onto the wound or into the wound if it is deep, after which it is covered with a gauze or bandage. Ointment or liniment can be applied either directly to the wound, or applied to gauze and cover the wound surface with it. After applying a powder, ointment or liniment to the wound, it is recommended to cover the wound surface with a gauze bandage. Powder, ointment or liniment is applied to the wound 1-4 times a day for 10-14 days.
Before applying the powder, liniment or ointment Streptocide, the wound should be washed with hydrogen peroxide or another disinfectant (for example, a solution of potassium permanganate, furacilin, etc.).
More about wounds
Ointment, liniment and powder most often provoke allergic reactions on the skin (urticaria, etc.) or dermatitis (rash, itching, burning of the skin) as a side effect. However, with prolonged use of an ointment, liniment or powder in large doses or for treating large wound surfaces, the active substance of Streptocide may be absorbed into the bloodstream with the development of systemic side effects, such as:
- Headache;
- Dizziness;
- Nausea;
- Vomit;
- Dyspeptic phenomena (belching, heartburn, diarrhea, constipation, etc.);
- Cyanosis (blanching or "blue" of the skin);
- Crystalluria (salt crystals in the urine);
- Impaired kidney function;
- Thyrotoxicosis (elevated levels of thyroid hormones in the blood);
- Leukopenia (decrease in the total number of leukocytes in the blood below normal);
- Agranulocytosis (complete absence of neutrophils, eosins and basophils in the blood);
- Thrombocytopenia (lower than normal levels of platelets in the blood);
- Hypoprothrombinemia (the level of prothrombin in the blood is below normal).
With the development of side effects of Streptocid, it is necessary to stop using the drug and consult a doctor.
- Individual hypersensitivity or allergic reactions to any components of the drug or to other drugs of the sulfonamide group;
- Anemia;
- Chronic heart failure;
- Hematopoietic disorders;
- thyrotoxicosis;
- kidney failure;
- Liver failure;
- Nephrosis;
- Nephritis;
- Porfiria;
- Azotemia - an increased level of nitrogenous compounds (urea, creatinine, etc.) in the blood;
- Deficiency of the enzyme glucose-6-phosphate dehydrogenase;
- The period of pregnancy and breastfeeding.
So, the following drugs are analogues of Streptocide in terms of therapeutic action:
- Argedin cream for external use;
- Argosulfan cream for external use;
- Dermazin cream for external use;
- Turmanidze ointment for external and local use;
- Mafenida acetate ointment for external use;
- Sulfadimezin tablets for oral administration;
- Sulfargin ointment for external use;
- Ebermin ointment for external use;
- Etazol tablets, solution for injection, granules for suspension for oral administration.
The reviews also indicate that Streptocid powder perfectly heals and disinfects a variety of wounds on the surface of the skin (for example, abrasions, cuts, non-healing umbilical wounds, calluses, surgical incisions after removal of warts, moles, etc.). Moreover, if the wounds are treated within a short period after their appearance, then a crust forms on them very quickly, and healing proceeds without complications, suppuration, weeping and without scarring. If the wounds fester, get wet and do not heal for a long time, then sprinkling them with Streptocide powder leads to a rapid cessation of the inflammatory process, the formation of a crust and subsequent healing.
The reviews also indicate that Streptocide powder is an excellent, highly effective treatment for acne and blackheads.
About the ointment and liniment of Streptocid, the reviews indicate that these are excellent means for treating various wound surfaces on the skin, leading to rapid crusting and healing.
- Powder 2 g, 1 sachet - 15 - 60 rubles;
- Powder 5 g, 1 sachet - 30 - 72 rubles;
- Ointment 10%, tube or jar 25 g - 50 - 80 rubles;
- Liniment 5%, tube or jar 30 g - 71 - 98 rubles.
Streptocid powder or Baneocin: what to do if you cut off a piece of your finger (folk recipe) - video
For wound healing, modern pharmacology offers a wide variety of tools and drugs. Each of them has its own characteristics, advantages and disadvantages, as well as certain indications for use.
But, despite the effectiveness of modern means, many doctors still prefer the old methods of treatment and drugs that have been proven for decades.
White sulfanilamide, which has the trade name "Streptocide", is one of the oldest and time-tested antimicrobial agents used in medicine since the middle of the last century.
The release of streptocide in any form in pharmacies is carried out without a doctor's prescription.
Of course, today this remedy is not used as often as in previous years, but at present, streptocide is already available not only in tablets, but also in the form of ointments, as well as in the form of a powder for external use.
With proper storage of streptocide, its shelf life is almost 10 years, while the drug has a very budgetary cost. Store the product in a place protected from moisture and sunlight, out of the reach of children.
Streptocide powder is a white, odorless, crystalline substance with a bitter taste. If earlier the drug was produced in tablets for internal use, from which powder for wounds was prepared by grinding, today the drug is intended exclusively for external use.
Its action is based on the fact that, getting on the surface of skin lesions, it begins to fight pathogenic microorganisms, disrupting their synthesis processes and stopping their spread.
Streptocide has a wide range of therapeutic effects, since it is highly effective in destroying:
- coli.
- Chlamydia.
- Staphylococcus.
- Streptococcus.
- Gonococcus.
- meningococci.
- Bacteria belonging to the group of typhoid-dysenteric pathogens.
- Toxoplasmosis.
The drug is also effective against a number of other pathogenic microorganisms and even against some varieties of helminths.
Streptocide powder can be used for external treatment:
- Wounds with different types of infection.
- Infected burns.
- Wound with purulent formations.
- Inflammation of the erysipelatous type.
- Furuncles (in the treatment of furunculosis).
- With various inflammatory processes, accompanied by the separation of pus in soft tissues.
In addition, streptocid in powder form is used in the treatment of throat diseases., such as tonsillitis, stomatitis, tonsillitis and various inflammatory processes, but its use for these purposes is no longer very common today, since modern pharmacology has an extensive list of drugs that are safer and more convenient to use.
When treating injuries, streptocid powder can be sprinkled on the wound, topically, but in no case should it be covered, especially a fresh injury.
Most often, the use of the drug is prescribed in cases where an active inflammation process is already underway in the wound, but in some cases the remedy can also be recommended as a prophylactic, for example, if there is a clear threat of infection and subsequent inflammation.
To treat the surface of the wound with streptocide powder, it is necessary to clean it of existing secretions and contaminants using sterile gauze swabs soaked in an antiseptic solution or hydrogen peroxide.
Cleaning is carried out several times if necessary. After treatment, the surface of the wound should be dried.
Streptocid for wounds is sprayed on the surface of an open wound with a thin layer, while capturing the skin area around the injury by about 2 cm. After applying the powder, it is necessary to apply a sterile breathable bandage to the wound.
Dressings will need to be changed three times a day, with the obligatory treatment and cleaning of the wound, applying a new layer of powder with each dressing change. Streptocid should be applied until the inflammatory process stops and the wound begins to heal.
It is important to correctly observe the dosage of the drug and remember that for a therapeutic effect, a large amount of powder should not be applied to the wound, since in this case the effect will be the opposite.
Powder should not be applied to a fresh wound, especially if it is large and deep. Streptocid powder greatly accelerates the healing process of wounds, while the tissues do not have time to recover properly, which leads to the formation of rough scars.
The dosage of streptocide in the treatment of wounds depends on the age of the patient.. For an adult, a single dose of the drug should not exceed 2 grams, while the maximum dose per day is up to 7 grams. In most cases, when treating a wound with streptocide, the maximum allowable dose is divided by 4 to 5 times and applied during the day with a mandatory change of dressings.
In the treatment of wounds after burns, streptocide in powder is used in an amount of 5-15 grams per day, dividing the dose into several times. In this case, the powder is applied to the surface of the burn by blowing it in, uniform spraying or powdering, avoiding areas of drug accumulation.
The use of streptocid powder shows high efficiency in the treatment of wounds of various origins, including those with an inflammatory-purulent process.
But it is important to remember that the drug has contraindications that must be considered when using the remedy.
Contraindications include:
- The patient has various types of anemia. Patients who have a pronounced decrease in hemoglobin levels, including those arising from serious blood loss, are prohibited from using streptocid to treat wounds.
- The presence of improper functioning of the kidneys, primarily their insufficiency.
- Porphyria, when there is a violation of pigmentation processes in the patient's body.
- Azotemia, in which a significant increase in nitrogenous substances is observed in the patient's blood.
It is important to remember that the treatment of any wound with streptocide in powder form should be carried out only with the appointment of a doctor and under his mandatory supervision.
The use of streptocide powder can be used to powder wounds and abrasions in children of various ages, subject to medical supervision of treatment, as well as mandatory compliance with the dosage.
It is important to remember that for infants under the age of 1 year, a single dose of streptocide should be no more than 0.1 grams and be applied no more than 3 times a day.
For children aged from one year to 5 years, a single dose with a three-time application of the drug to the wound should not exceed 0.4 grams.
For children from 5 years old and adolescents up to 18 years old, the dose per application is not more than 0.5 grams and up to 4 dressings per day are allowed with mandatory processing.
Pregnant women should not use the drug even in small doses., since when it enters the bloodstream, the substance easily penetrates the placental barrier and can adversely affect the development of the baby, especially in the first third of the gestation period. Therefore, during pregnancy, it is best to give preference to other means that are safe for the fetus and the expectant mother, but only a doctor should prescribe them.
The closest analogues of streptocide in powder form in structural terms can be called streptocide tablets, when crushed, you can get a therapeutic powder, as well as white streptocide and sulfamide in its pure form. In addition, a streptocide-based ointment is also produced, which is also used to heal wounds and various skin lesions.
There are many analogues of streptocide for therapeutic action, among which are many types of powder powders for the treatment of wounds, as well as some ointments, for example: Sulfargin, Mafenida, Argedin, Sulfadimezin, Agrosulfan, Turmanidze composition, Etazol (in all forms), Ebermin, Dermazin.
Akriderm cream, Berodual solution, Celederm cream, Sunoref ointment, Leniment Synthomycin can also be attributed to analogues.
It is important to remember that it is possible to replace the main drug with analogues, both structural and therapeutic, only with the permission of the doctor who prescribed the treatment with the use of streptocide in powder form.
Streptocide is a broad-spectrum antibacterial agent characterized by bacteriostatic action against gonococci, streptococci, meningococci, pneumococci, Escherichia coli and other bacteria.
The active substance - Sulfanilamide - has a bacteriostatic effect. The mechanism of action is due to competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to a disruption in the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, to a disruption in the synthesis of nucleic acids.
Active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.
Streptocid powder has a crystalline structure and white color. Contains the main active ingredient sulfanilamide in the amount of 2 g. The powder is packaged in laminated sachets of 2 g.
When applying the powder to the skin in the area of a wound or inflammatory process, the active ingredient of the drug can be partially absorbed into the systemic circulation. It is evenly distributed in tissues, passes through the blood-brain and placental barrier. It is metabolized mainly in the liver with the formation of inactive decay products that are excreted from the body in the urine.
Indications for use
What helps Streptocide powder? According to the instructions, the drug is prescribed in the following cases:
- tonsillitis;
- purulent-inflammatory skin lesions;
- infected wounds of various etiologies (including ulcers, cracks);
- furuncle;
- carbuncle;
- pyoderma;
- folliculitis;
- erysipelas;
- acne vulgaris (pimples);
- impetigo;
- burns (1 and 2 degrees).
Streptocide in the form of a powder is used for the etiotropic treatment of infectious and inflammatory skin diseases caused by microorganisms sensitive to sulfanilamide.
Instructions for use Streptocid, dosage of powder and tablets
The powder is intended for external use. With a shallow skin lesion, Streptocid is applied in a thin layer directly to the area of \u200b\u200bthe pathological process.
For deep wounds, the instruction for the use of Streptocide powder recommends introducing the powder into its cavity, additionally grinding if necessary. The duration of treatment is determined individually.
In bacillary and coccal diseases, the drug is used orally (tablets). The dosage for adults is 500 to 1000 mg 4 to 6 times a day.
In case of wound infections with a purulent complication, for the treatment of infected burns, the introduction of a powder, liniment or Streptocide ointment into the wound is prescribed.
The maximum dose for adults when taken orally: single 2 g, daily - 7 g.
At the moment, there is no streptocide in the dosage form for internal use, only external. You cannot take it inside.
special instructions
Myelotoxic agents increase the manifestations of hematotoxicity of the drug.
Side effects
The instruction warns of the possibility of developing the following side effects when using Streptocide powder:
- From the digestive system: nausea, vomiting, diarrhea.
- From the hemopoietic system: rarely - eosinophilia, thrombocytopenia, leukopenia, hypoprothrombinemia, agranulocytosis.
- From the side of the central nervous system and peripheral nervous system: in isolated cases - blurred vision, headache, dizziness, peripheral neuropathy, ataxia.
- Other: skin allergic reactions; rarely - nephrotoxic reactions (most likely in patients with impaired renal function); in isolated cases - hypothyroidism.
Contraindications
It is contraindicated to prescribe Streptocide in the following cases:
- severe renal failure;
- blood diseases;
- deficiency of glucose-6-phosphate dehydrogenase;
- nephrosis;
- jade;
- acute porphyria;
- thyrotoxicosis;
- 1st and 2nd trimesters of pregnancy;
- lactation;
- hypersensitivity to sulfonamides.
Overdose
Overdose symptoms observed when administered orally are nausea, vomiting, dizziness, headache, cyanosis.
It is recommended to wash the stomach with a 2% solution of sodium bicarbonate, inside - a suspension of activated carbon, other enterosorbents. Plentiful drinking, intravenous drip administration of sodium bicarbonate are shown. In severe cases - forced diuresis, hemodialysis.
Analogues Streptocid, price in pharmacies
If necessary, you can replace Streptocide with an analogue for the active substance - these are drugs:
- Osarcid;
- Streptocide white;
- Streptocid white soluble;
- Streptocide soluble;
- Streptocid ointment 10%;
- Sulfanilamide;
- Streptonitol.
Analogues by ATX code:
- Streptocid white,
- Streptocide tablets.
When choosing analogues, it is important to understand that the instructions for using Streptocid powder, price and reviews, do not apply to drugs of similar action. It is important to consult a doctor and not to make an independent replacement of the drug.
Price in Russian pharmacies: Streptocid 2g powder for external use - from 23 to 39 rubles, the cost of ointment 10% 25 g - from 64 rubles, according to 693 pharmacies.
Keep out of the reach of children in the original packaging at a temperature not exceeding 25 °C. Shelf life - 5 years.
Terms of dispensing from pharmacies - without a prescription.